What is the output if you do:
sudo systemctl status wpa_supplicant.service
sudo systemctl disable --now wpa_supplicant.service
sudo systemctl status wpa_supplicant.service
If you think that after that, it gets enabled again at some point, get once again the output of sudo systemctl status wpa_supplicant.service
However, these systemctl commands should work on Silverblue the same way as on Workstation.
Well, first, if I read it correctly, you are not working with sudo but a dedicated root account?
Second, I cannot fully exclude a difference at Silverblue as I have never worked with acpitool on it, but /proc/ is a virtual file system for real time kernel and process information. It should not be affected by the immutable nature of Silverblue.
My first guess is that this is a device on which your system depends on. How does it work with other devices? Do you have this error at all devices?
Additionally, may I ask, in order to fully understand your acpitool -W 8 command, what is the output of acpitool -w ?
Also, you may follow the development in the other thread: Freeze after wake from suspend → You could try to disable the bluetooth service (I see in your logs it is activated) and check if that makes a difference. This could offer direction concerning the cause and help us to evaluate how to proceed.