Comparing Fedora core os to Fedora silverblue

Is Fedora Core os comparitively more secure when compared to fedora silverblue itself. How compatible is Fedora core os with different application softwares and virtual machine managers

It makes no sense to compare them because they are a different type of operating systems.

Silverblue you will run on a workstation as an atomic-desktop. Silverblue is just the gnome desktop made as a immutable system. Fedora Silverblue | The Fedora Project

While core os is running on container applications, as the name says , as the core os. The container optimized OS | The Fedora Project