In other words, it’s used by GTK applications that display some kind of web-based content. Many apps nowadays use web technologies to display parts of their UI or content, even if it doesn’t look like a web browser.
You can follow the trail of dependencies on your system, using some dnf commands. Here’s what it looks like on my system:
If you try to remove it, dnf will tell you what other packages will be removed. Whether it’s “safe” or not depends on if you want those other packages.
If you’re not sure, you can post the full output of the remove command here.