My system had two drives one SSD with boot and root partition and the home partition on a Sata drive, sata drive had to be replaced so took it out and remove from /etc/fstab and reboot no problem so far, except on boot it continue to look for old drive
/dev/mapper/luks-fe60dc59-38a2-4910-b14c-fd3fb4f87d1d / xfs defaults,x-systemd.device-timeout=0 0 0
UUID=24c19213-7a4e-4306-bb25-24590779206e /boot xfs defaults 0 0
#/dev/mapper/luks-7d7ac6a9-b5ad-4282-9668-d40f326b2cc7 /home ext4 defaults,x-systemd.device-timeout=0 1 2
UUID=c90200fb-7af2-43ba-8b08-9e76af4bbb38 /home xfs defaults,x-systemd.device-timeout=0 1 2
/dev/mapper/luks-3ead2b4b-5f37-4d3b-bc27-b02a5fd2d665 swap swap defaults,x-systemd.device-timeout=0 0 0
On boot it keep trying to load the old drive
A start job is running for dev-disk-by\x2duuid-7d7ac6a9\x2db5ad\x2d4282\x2d9668\x2dd40f326b2cc7.device
Any help appreciated