Edit: Root cause + workaround:
After some digging this is a systemd bug.
Fix is to downgrade systemd 257. Check your dependencies on systemd 258, for example, gdm 49.1.0 depends on systemd 258, to downgrade to systemd 257 you’d need to downgrade gdm to 49.0.1.
Fix is to downgrade systemd 257. Check your dependencies on systemd 258, for example, gdm 49.1.0 depends on systemd 258, to downgrade to systemd 257 you’d need to downgrade gdm to 49.0.1.
+1 on this issue with Fedora 43 and Nvidia 4070 Ti Super, driver version 580.105.08. I have just disabled auto suspend for now.
May not be related, but since upgrading to Fedora 43, I’ve noticed another issue - screen blanking no longer works when Firefox is running (146.0b9 developer edition).