Dual Monitor Gaming

Hello! I am new here and I would like to describe my problem. I have been distro-hopping for quite a long time and I actually want to stay with fedora. I use fedora mainly for gaming and there I have a small but not insignificant problem. In certain games the mouse jumps to the second monitor, which can be fatal in some games (e.g. League of Legends). Since I have tested many Arch-based distro I know that it is quite possible to catch mouse and I absolutely do not know why. Is it because of:

GPU driver?

do I need to make any setting?

thx and regards