I’ve noticed this when doing my illustration work (whom i got screwed upon because of this).
Changing color profiles doesn’t do anything, and, trying to import new ones, also refuses to work.
My hypothesis was night light but nope.
I need help so i can work 
Welcome to Fedora @wesweswes , we can’t help you if you not tell us where, when and what not works.
If I would like to help you search a solution, at least I would need some search key words 